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Cat. No. | Product Name | Target | Signaling Pathways |
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T5146 |
Eptifibatide acetate (148031-34-9 free base)
Eptifibatide acetate,依菲巴特醋酸盐 |
Others | Others |
Eptifibatide acetate (148031-34-9 free base) (Eptifibatide acetate) 是一种糖蛋白 IIb/IIIa 抑制剂类的抗血小板药物,是一种由 6 个氨基酸和一个巯基丙酰基残基构成的环状七肽。 | |||
T5020 |
Eptifibatide
Eptifibatide Acetate,Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2,依替巴肽 |
Others | Others |
Eptifibatide (Eptifibatide Acetate) 是一种糖蛋白 IIb/IIIa 抑制剂类的抗血小板药物,是一种由 6 个氨基酸和一个巯基丙酰基残基构成的环状七肽。 | |||
TP1989L |
Nogo-66 (1-40) aceate ( 475221-20-6 Free base)
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Nogo-66 (1-40) aceate (475221-20-6 Free base) 是对应于 Nogo-66 残基 1 - 40 的肽片段,Nogo-66 是抑制轴突生长的髓磷脂蛋白 Nogo 的结构域。Nogo-66 (1-40) aceate 作为 Nogo-66 受体 (NgR) 的竞争性拮抗剂,阻断 Nogo-66 和 CNS 髓磷脂诱导的轴突生长抑制,但不会减少髓磷脂相关糖蛋白 (MAG) 体外抑制神经突生长。Nogo-66 (1-40) aceate 促进体内脊髓损伤后半切脊髓轴突的再生和运动恢复。 | |||
T83947 |
HDAC4 CHDI Degrader 11
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HDAC4 CHDI Degrader 11是一种高效且选择性的HDAC4降解剂(PROTAC),其在Jurkat E6-1细胞和Jurkat细胞中的DC50值分别为4 nM和6 nM。该化合物由类IIa HDAC抑制剂三氟甲基噁二唑通过连接体与Von Hippel-Lindau (VHL) 蛋白的配体连接而成。在亨廷顿病小鼠细胞模型中,HDAC4 CHDI Degrader 11能强效地降解HDAC4(DC50= 1nM)。在神经母细胞瘤细胞系中,可与P-糖蛋白抑制剂Elacridar联用以实现更有效的降解。 | |||
T37843 |
Australine (hydrochloride)
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Australine is a pyrrolizidine alkaloid originally isolated fromC. australethat has enzyme inhibitory activities.1,2,3It is an inhibitor of glucoamylase (IC50= 5.8 μM) that also inhibits glucosidase I, sucrase, maltase, andA. nigerα-glucosidase (IC50s = 20, 28, 35, and 28 μM, respectively).2,3Australine is selective for these enzymes over glucosidase II, α- and β-mannosidase, and α- and β-galactosidase up to 500 μM, β-glucosidase, with only 5% inhibition at 66 μM, as well as isomaltase and trehal... | |||
T36847 |
Coelenterazine hcp
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Coelenterazine hcp is a synthetic bioluminescent luciferin that displays an emission maximum of 445 nm.1It has been used as a calcium indicator and substrate to quantifyRenillaluciferase activity.1,2,3 1.Sabnis, R.W.Handbook of biological dyes and stains: Synthesis and industrial applications(2010) 2.Shimomura, O., Kishi, Y., and Inouye, S.The relative rate of aequorin regeneration from apoaequorin and coelenterazine analoguesBiochemistry Journal296(Pt 3)549-551(1993) 3.Pichler, A., Prior, J.L.,... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T2S0223 |
Isosinensetin
异橙黄酮,6-Demethoxynobiletin |
Antioxidant; HIV Protease; Antibacterial; P-gp | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; oxidation-reduction; Proteases/Proteasome |
Isosinensetin (6-Demethoxynobiletin) 是从青皮中提取的一种甲氧基黄酮,具有抗氧化和抑制 HIV-1 蛋白酶的活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01190 |
GPVI Protein, Human, Recombinant (His)
Glycoprotein 6,Gp6,MGC13816 |
Human | HEK293 Cells |
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands. ... | |||
TMPJ-00605 |
GPVI Protein, Mouse, Recombinant (His)
Glycoprotein 6,GP6,glycoprote... |
Mouse | HEK293 Cells |
Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregation and thrombin generation. GPVI is also a secondary receptor required for platelet spreading on laminin. GPVI associates with the Fc receptor gamma -chain via charged aa in the TM domains of GPVI (arginine) and the FcR gamma (aspartic acid). Collagen binding by the GPVI Ig-like... | |||
TMPK-01302 |
GPVI Protein, Cynomolgus, Recombinant (His)
Glycoprotein 6,MGC138168,GPVI,Gp<... |
Cynomolgus | HEK293 Cells |
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands. ... | |||
TMPY-02891 |
PSG6 Protein, Human, Recombinant (His)
PSG12,PSG6,PSBG-6,pregnancy specific β-1-<... |
Human | Baculovirus Insect Cells |
PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived fr... | |||
TMPY-00994 |
MOG Protein, Human, Recombinant (aa 30-149, His)
NRCLP7,BTNL11,myelin oligodendrocyte glycoprotein,B... |
Human | E. coli |
MOG Protein, Human, Recombinant (aa 30-149, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15 kDa and the accession number is Q16653-1. | |||
TMPK-00644 |
CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47,OA3,IAP,CD47 molecule,CD47 glycoprotein,MER |
Cynomolgus,Rhesus | HEK293 Cells |
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers. | |||
TMPJ-00291 |
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
IL-6R-α,IL-6R-alpha,Interleukin-6... |
Human | HEK293 Cells |
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an... | |||
TMPH-01452 |
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc)
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HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc) is expressed in E. coli. | |||
TMPH-01453 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Glycoprotein U22 (His)
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HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Glycoprotein U22 (His) is expressed in in vitro E. coli expression system. | |||
TMPH-01451 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Envelope glycoprotein B (His & Myc)
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HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Envelope glycoprotein B (His & Myc) is expressed in E. coli. | |||
TMPJ-01092 |
MGAT2 Protein, Human, Recombinant (His)
Alpha-1,Mannoside Acetylglucosaminyltransferase 2,6... |
Human | HEK293 Cells |
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A. | |||
TMPH-01456 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc)
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HHV-6B | E. coli |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc) is expressed in E. coli. | |||
TMPJ-01467 |
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
Oncostatin-M,OSM |
Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac... | |||
TMPK-01358 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01364 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84,CD172... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00101 |
IL-6 Protein, Cynomolgus, Recombinant (His)
CDF,BSF-2,白介素,IL6,HGF,白细胞介素,Interleukin-6,... |
Cynomolgus | HEK293 Cells |
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. | |||
TMPK-01042 |
FcRH6/FCRL6 Protein, Human, Recombinant (His)
Fc receptor homolog 6,IFGP6,FcR-like prote... |
Human | HEK293 Cells |
Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed that FCRL6 expression by NK- and T-cell subpopulations increases as a function of differentiation and is remarkably restricted to mature lymphocytes with cytotoxic capability. | |||
TMPY-02800 |
CGB7 Protein, Human, Recombinant (His)
chorionic gonadotropin beta subunit 7,chorionic gonadotropin... |
Human | Baculovirus Insect Cells |
CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CGB7 gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are... | |||
TMPJ-00385 |
CDH6 Protein, Human, Recombinant (hFc)
K-Cadherin,Cadherin-6,CDH6,Kidney Cadherin |
Human | HEK293 Cells |
Cadherin-6 (CDH6) is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as a 790 aa type I transmembrane glycoprotein that contains a 18 aa signal peptide, a 35 aa propeptide, a 562 aa extracellular region, a 21 aa transmembrane segment, and a 154 aa cytoplasmic domain. There are five cadherin domains of approximately 110 aa each in the extracellular r... | |||
TMPJ-00086 |
CT-1 Protein, Human, Recombinant (His)
CTF1,CT-1,Cardiotrophin-1 |
Human | E. coli |
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and... | |||
TMPH-01080 |
Ceruloplasmin Protein, Human, Recombinant (His & Myc)
CP,Ceruloplasmin,Ferroxidase ceruloplasmin,Cuproxidase cerul... |
Human | E. coli |
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense. Ceruloplasmin Protein, Human, Recombinant (His & Myc) is expressed in E. co... | |||
TMPY-01856 |
MGAT5 Protein, Human, Recombinant (His)
mannosyl (alpha-1,6-)-glycoprotein β-1, |
Human | HEK293 Cells |
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, also known as Alpha-mannoside beta-1,6-N-acetylglucosaminyl-transferase, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V, MGAT5, and GGNT5, is a single-pass type II membrane protein that belongs to the glycosyltransferase 18 family. MGAT5 / GGNT5 catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of t... | |||
TMPY-03611 |
PMM2 Protein, Human, Recombinant (His)
CDG1a,phosphomannomutase 2,PMM2,CDGS,CDG1,PMI,PMI1 |
Human | E. coli |
Phosphomannomutase 2, also known as PMM2 and CDG1, belongs to the eukaryotic PMM family. Phosphomannomutase 2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mannose 1-phosphate is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. GDP-mannose can transfer its small sugar molecule called mannose to the growing oligosaccharide chain. Once the correct number of small sugar molecules are linked together to form the oligosaccharide, it c... | |||
TMPJ-00136 |
MBL2 Protein, Human, Recombinant (His)
Collectin-1,Mannose-Binding Lectin,COLEC1,Mannan-Binding Pro... |
Human | HEK293 Cells |
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These h... | |||
TMPJ-01361 |
Siglec-8 Protein, Human, Recombinant (mFc)
CD329 antigen,Siglec-8,SAF2SAF-2,CDw329,Siglec8,SAF-2,SAF2 |
Human | HEK293 Cells |
Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c... | |||
TMPJ-00567 |
NCR1 Protein, Human, Recombinant (hFc)
hNKp46,Natural cytotoxicity triggering receptor 1,N... |
Human | HEK293 Cells |
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow. | |||
TMPK-00614 |
NKp46/NCR1 Protein, Human, Recombinant (His)
NKp46,MAR-1,Ly94,NCR1,NKP46FLJ99094,CD335 |
Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 27.5 kDa and the accession numb... | |||
TMPY-03010 |
NRG1 beta 1 Protein, Human, Recombinant
NDF,GGF,MSTP131,Neuregulin 1,MST131,ARIA,NRG1-IT2,SMDF,NRG1 ... |
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6. | |||
TMPK-00615 |
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD335,NCR1,NKp46,NKP46FLJ99094,Ly94,MAR-1 |
Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we... | |||
TMPJ-00827 |
Tau-D Protein, Human, Recombinant (His)
PHF-Tau,MAPTL,MAPT,Paired Helical Filament-Tau,Microtubule-A... |
Human | E. coli |
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective,... | |||
TMPY-03128 |
LAIR1 Protein, Mouse, Recombinant (hFc)
leukocyte-associated immunoglobulin-like receptor 1,BB1152 |
Mouse | HEK293 Cells |
LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6. | |||
TMPY-04277 |
CD45 Protein, Mouse, Recombinant (hFc)
Cd45,protein tyrosine phosphatase, receptor type, C,Ly-5,L-C... |
Mouse | HEK293 Cells |
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6. | |||
TMPY-05798 |
VEGF145 Protein, Human, Recombinant
血管内皮生长因子,vascular endothelial growth factor A,VPF,MVCD1,VEGF... |
Human | HEK293 Cells |
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6. | |||
TMPY-02600 |
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
neuregulin 1,HRGA,NRG1 β1,HGL,MST131,MSTP131,HRG,ARIA,NDF,GG... |
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6. | |||
TMPY-02705 |
NRG1 beta 1 Protein, Human, Recombinant (hFc)
MSTP131,HRG1,NRG1-IT2,ARIA,HGL,SMDF,GGF,HRG,NDF,MST131,neure... |
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6. |